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Thursday, Feb. 16 , 7:30 a.m.-7:30 p.m.

7:30 a.m.-9:00 a.m.            

Session I:  Concurrent Symposia A
 
  CT Angiography and Perfusion:  Enhancing Decision Making in the Emergency Department
 Moderators: Wade Smith, San Francisco, California
  Ting-Yim Lee, London, ON, Canada
  Overview of Predictive Capabilitiesof the CTA, CTA Source Image, and CT Perfusion in Acute Ischemic Stroke
  Michael H. Lev, Boston, Massachusetts
  CT Perfusion:  Hardware, Software, and Quantitative Perfusion Maps - Present and Future
  Ting-Yim Lee, London, ON, Canada
  Comparison of CT and MRI Imaging Techniques in Acute Stroke
  Peter Schramm, Heidelberg, Germany
  The Clinical Utility of Advanced CT Techniques in the Management of Acute Stroke Results from STOP - Stroke Study
Karen L. Furie, Boston, Massachusetts
Discussion
   
7:30-9:00 a.m. Session I:  Concurrent Symposia B 
Manipulating the Biology of Axonal Outgrowth In the Central Nervous System to Improve Recovery after Stroke
Moderators: Walter J. Koroshetz, Boston, Massachusetts
Rajiv R. Ratan, White Plains, New York
Inosine as a Promoter of Neural Outgrowth From Bench to Clinical Trial
Larry Benowitz, Boston, Massachusetts
Proteoglycans and Brain Repair
Marty Grumet, Piscataway, New Jersey
Double Inhibition for Benefit in Stroke Inhibiting Inhibition of Neurite Outgrowth
Stephen M. Strittmatter, New Haven, Connecticut
Clinical Trial Designs to Test Stroke Recovery Drugs
Walter J. Koroshetz, Boston, Massachusetts
Discussion
7:30-9:00 a.m.  Session I:  Concurrent Symposia C 
  Getting Ready for Stroke Center Certification
Moderator: Edward C. Jauch, Cincinnati, Ohio
Overview of Primary Stroke Center Certification Introduction and JCAHO Certification Center
Mark J. Alberts, Chicago, Illinois
Organizing Your Stroke Team
Anne D. Leonard, San Antonio, Texas
Preventing In-hospital Complication of Stroke
Lee H. Schwamm, Boston, Massachusetts
Conducting Research at Your Stroke Center
Joseph P. Broderick, Cincinnati, Ohio
Discussion
 
7:30-9:00 a.m.  Session I:  Concurrent D 
  Prevention Oral Abstract Presentations 
Moderators: S. Claiborne Johnston, San Francisco, California
Bruce Ovbiagele, Los Angeles, California
3 Intracranial Stenosis, “Failure” of Antithrombotic Therapy, and Risk of Stroke 
Lucian Maidan, Emory Univ, Atlanta, GA; Michael Lynn, Rollins School of Public Health, Atlanta, GA; George Cotsonis, Emory Univ, Rollins School of Public Health, Atlanta, GA; Timothy Upchurch, Emory Univ, Atlanta, GA; Steven Levine, Mount Sinai School of Med, New York, NY; Jose Romano, Univ of Miami, Miami, FL; Marc Chimowitz, Emory Univ, Atlanta, GA; for the WASID investigators 
4 Patient Subgroups in the Randomized SAPPHIRE Study of Carotid Stenting with Distal Protection vs Endarterectomy 
Pierre B Fayad, Univ of Nebraska Med Ctr, Omaha, NE; Kenneth Ouriel, Cleveland Clinic Foundation, Cleveland, OH; Marc Wholey, Allegheny Univ Hosp, Cleveland, OH; Barry Katzen, Miami Cardiac and Vascular Inst, Miami, FL; Sidney Cohen, Cordis, Warren, NJ; Jay Yadav, Cleveland Clinic Foundation, Cleveland, OH 
5 Paradoxical Rebound Platelet Activation After NSAIDS or COX-2 Inhibitor Withdrawal: Which Patients Are at Higher Risk for Vascular Events? 
Victor Serebruany, Alex Malinin, HeartDrug Research, Towson, MD; Deepak Bhatt, Cleveland Clinic, Cleveland, OH
6 Local TV News Reporting of Stroke: A National Perspective 
James M Pribble, Jennifer J Majersik, William G Barsan, Lewis B Morgenstern, Univ of Michigan, Ann Arbor, MI 
7 Sarpogrerale-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS): A Randomized, Double-Blind, Aspirin-Controlled Trial 
Yukito Shinohara, Ctr for Stroke and Neurological Diseases, Tokai Univ, Tokyo Hosp, Tokyo, Japan; Hideo Tohgi, Iwate Med Univ, Morioka, Japan; Yasuo Fukuuchi, Ashikaga Red Cross Hosp, Ashikaga, Japan; Shinichiro Uchiyama, Tokyo Women's Med Univ, Tokyo, Japan; Takenori Yamaguchi, National Cardiovascular Ctr, Osaka, Japan; Shotai Kobayashi, Shimane Univ Faculty of Med, Izumo, Japan; Eiichi Otomo, Yokufukai Geriatric Hosp, Tokyo, Japan; Fumio Gotoh, Keio Univ, Tokyo, Japan; Shunsaku Hirai, Kunihiko Hayashi, Gunma Univ, Maebashi, Japan; Tohru Sawada, Aino Hosp, Osaka, Japan; Akiro Terashi, Nippon Med School, Tokyo, Japan; Shunnosuke Handa, Tokai Univ, Tokyo, Japan; Kazuoki Kondo, Mitsubishi Pharma Corp, Tokyo, Japan; Katsuya Nishimaru, Fukuoka Univ, Fukuoka, Japan 
1 1-Year Restenosis After Carotid Stenting in the Lead-in Phase of the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST)
Helmi L Lutsep, Oregon Stroke Ctr, OHSU, Portland, OR; George Howard, Virginia J Howard, Jenifer Voeks, Univ of Alabama at Birmingham, Birmingham, AL; Wayne M Clark, Oregon Stroke Ctr, OHSU, Portland, OR; Alice Sheffet, UMDNJ-New Jersey Med School, Newark, NJ; Thomas G Brott, Mayo Clinic Jacksonville, Jacksonville, FL; Robert W Hobson II, UMDNJ-New Jersey Med School, Newark, NJ; for the CREST Investigators
2 Low Complication Rates for Carotid Artery Stenting in the Credentialing Phase of the Carotid Revascularization Endarterectomy Versus Stenting Trial
Gary Roubin, Lenox Hill, New York, NY; Wayne Clark, Oregon Stroke Ctr, Portland, OR; Elie Chakhtoura, St Michael's Med Ctr, Newark, NJ; William Brooks, Central Baptist Hosp, Lexington, KY; Robert J Hye, Kaiser Permanente, San Diego, CA; Virginia Howard, Univ of Alabama, Birmingham, AL; Susan Hughes, MeeLee Tom, UMDNJ/New Jersey Med School, Newark, NJ; Jamie Roberts, Mayo Clinic, Jacksonville, FL; Larry B Goldstein, Duke Univ, Durham, NC; Thomas Brott, Mayo Clinic, Jacksonville, FL; Robert W Hobson II, UMDNJ/New Jersey Med School, Newark, NJ 
Discussion
   
9:00- 9:10 a.m.  Break 
   
9:10-10:40 a.m.  Session II:  Concurrent Symposia A 
  Vascular Cognitive Impairment and Stroke Trials:  Time for Meeting of the Minds 
Moderators:  Vladimir Hachinski, London, ON, Canada
  Colin P. Derdeyn, St. Louis, Missouri
  The Physiology of Vascular Cognitive Impairment:  Atherosclerosis, Blood Pressure, and Cerebral Ischemia 
  Randolph S. Marshall, New York, New York
  Failing Heart, Failing Brain?  CHF, CABG, and Cognitive Outcomes
  Patrick Pullicino, Newark, New Jersey 
  Large and Small Vessel Stroke: Tailoring the Battery to the Disease 
  Ronald M. Lazar, New York, New York 
  Incorporating Cognitive Outcomes in Stroke Trial Design:  Past and Future Measurement 
  David Nyenhuis, Chicago, Illinois
  Discussion 
   
9:10-10:40 a.m.  Session II:  Concurrent Symposia B 
  Beyond Glutamate: Novel Mechanisms and Targets for Ionic Imbalance and Neuroprotection 
Moderators:  Michael A. Moskowitz, Charlestown, Massachusetts
  Mark P. Goldberg, St. Louis, Missouri
  Introduction 
  Michael A. Moskowitz, Charlestown, Massachusetts
  Transient Receptor Potential Channels and PSD Proteins 
  Michael Tymianski, Toronto, Ontario, Canada
  pH-sensitive Channels 
  Roger P. Simon, Portland, Oregon 
  Proteases and Ion-Exchange Transporters
  Perluigi Nicotera, Leicester, United Kingdom 
  Beyond Glutamate:  Perspectives and Predictions 
  Alastair Buchan, Oxford, United Kingdom
  Discussion 
   
9:10-10:40 a.m.  Session II:  Concurrent Symposia C 
  Preventing Strokes and Improving Outcomes
Moderator: Arthur M. Pancioli, Cincinnati, Ohio
Medical Approaches to Stroke Prevention
Larry B. Goldstein, Durham, North Carolina
Surgical and Endovascular Treatments for Stroke Prevention
Ralph L. Sacco, New York, New York
The Role of Nurses and Allied Health Professionals in Stroke Prevention and Recovery
name to come
Advances in Rehabilitation
Richard D. Zorowitz, Philadelphia, Pennsylvania
Discussion
   
9:10-10:40 a.m.  Session II:  Concurrent D 
  Thrombolysis Oral Abstract Presentations 
Moderators: Devin L. Brown, Ann Arbor, Michigan
Adnan I Qureshi, Newark, New Jersey
8 Efficacy of Microbubble-Enhanced Sonothrombolysis Among Stroke Subtypes 
Marta Rubiera, Marc Ribo, Raquel Delgado-Mederos, Esteban Santamarina, Rafael Huertas, Pilar Delgado, Joan Montaner, José Alvarez-Sabín, Carlos A Molina, Hosp vall d´Hebron, Barcelona, Spain 
9 "Mild Stroke" Should Not Exclude Patients from Thrombolytic Therapy 
Nicole R Gonzales, Karen C Albright, Elizabeth A Noser, Aslam M Khaja, Hashem M Shaltoni, Adam Romman, Neal Zimbaldi, Mary S Baraniuk, Lemuel A Moye, James C Grotta, Univ of Texas Med School, Houston, TX 
10 National US Estimates of rtPA Use: ICD-9 Codes Substantially Underestimate 
Dawn Kleindorfer, Christopher Lindsell, Univ of Cincinnati, Cincinnati, OH; Greg White, Tonja Curtis, Johnson and Johnson Inc, New Brunswick, NJ; Lawrence Brass, Yale Univ, New Haven, CT; Walter Koroshetz, Massachusetts General Hosp, Boston, MA; Joseph P Broderick, Univ of Cincinnati, Cincinnati, OH 
11 Robust Confirmation of Treatment Effect by Baseline Severity-Adjusted End Point Reanalysis of the NINDS-tPA Stroke Trials 
Jeffrey L Saver, Banafsheh Yafeh, UCLA Stroke Ctr, Los Angeles, CA 
12 Vessel Size Explains Gender Differences in Response to Intravenous Thrombolysis for Acute Stroke
David S Liebeskind, Amelia L Laughton, Doojin Kim, Sidney Starkman, Noriko Salamon, J Pablo Villablanca, Jeffrey L Saver, UCLA, Los Angeles, CA 
13 Microcatheter Contrast Injections During Intra-arterial Thrombolysis Increase Intracranial Hemorrhage Risk 
Pooja Khatri, Joseph P Broderick, Jane C Khoury, Janice Carrozzella, Thomas Tomsick, Univ of Cincinnati, Cincinnati, OH; IMS-1 and 2 Investigators 
14 Acute Stroke Management in the Elderly 
Neer Zeevi, Univ of Connecticut, Hartford, CT; Nora Lee, Isaac Silverman, Hartford Hosp, Hartford, CT; Louise McCullough, Univ of Connecticut, Hartford, CT 
Discussion
   
10:40-11:10 a.m. Exhibits/Break
11:10 a.m.-12:45 p.m. Session III:  Plenary Session I
Moderators: Costantino Iadecola, New York, New York
Philip B. Gorelick, Chicago, Illinois
  Conference Opening 
Costantino Iadecola, New York, New York
American Heart Association/American Stroke Association President's Remarks
Robert H. Eckel, Denver, Colorado
Thomas Willis Lecture
Michael A. Moskowitz, Charlestown, Massachusetts
Plenary Symposium
The Asymptomatic Vascular Lesion and Prevention of Stroke:  When to Diagnose and When to Treat in 2006
Moderators: Thomas G. Brott, Jacksonville, Florida
John D. Barr, Memphis, Tennessee
The Stenotic, Asymptomatic Plaque in the High-risk Patient
Werner Hacke, Heidelberg, Germany
The Unruptured Cerebral Aneurysm
Jean Raymond, Montreal, PQ, Canada
The Unruptured Cerebral Arteriovenous Malformation
Robert D. Brown, Jr., Rochester, Minnesota
The Patient Foramen Ovale
Anthony Furlan, Cleveland, Ohio
12:45-2:00 p.m. Exhibits and Lunch Break
Nursing and Rehabilitation Professions Roundtable Luncheon
(ticket required, seating is limited)
Early Career/ Stroke Leader Luncheon
(ticket required, seating is limited)
2:00-3:30 p.m. Session IV:  Concurrent Symposia A
Mother and Child:  Increased Risk of Stroke in the Puerperium
Moderators: Donna M. Ferriero, San Francisco, California
Gabrielle de Veber, Toronto, Ontario, Canada
Clinical Recognition of Ischemic Stroke and Venous Thrombosis in Fetus and Neonate
Meredith R. Golomb, Indianapolis, Indiana
Stroke During Childbirth:  More Common Than Thought
Cheryl Bushnell, Durham, North Carolina
Fetal and Neonatal Neuroimaging - Identifying the Stroke as it Happens
Ellen Grant, Boston, Massachusetts
Maternal Risk Factors for Perinatal Stroke
Yvonne Wu, San Francisco, California
Discussion
2:00-3:30 p.m. Session IV:  Concurrent Symposia B
Brain Stimulation to Improve Stroke Outcome
Moderator:  Steven C. Cramer, Orange, California
Introduction
Steven C. Cramer, Orange, California
  Stimulation and Motor System Plasticity in Primates
  Randolph J. Nudo, Kansas City, Kansas
  Cortical Stimulation in Human Neurorehabilitation 
  Friedhelm Hummel, Tuebingen, Germany
  Repetitive TMS in the Treatment of Stroke 
  Alvaro Pascual-Leone, Boston, Massachusetts
  Human Trials of Epidural Motor Cortex Stimulation 
  Richard L. Harvey, Chicago, Illinois
  Discussion 
   
2:00-3:30 p.m.  Session IV:  Concurrent C 
  Hemorrhage Oral Abstract Presentations 
Moderators: Daniel Woo, Cincinnati, Ohio
Gavin W. Britz, Seattle, Washington
15 The Increasing Burden of Anticoagulant-Associated Intracerebral Hemorrhage 
Matthew L Flaherty, Mary Haverbusch, Padmini Sekar, Brett M Kissela, Dawn Kleindorfer, Charles J Moomaw, Laura Sauerbeck, Joseph P Broderick, Daniel Woo, Univ of Cincinnati, Cincinnati, OH 
16 Early Hematoma Evacuation After Fibrinolysis in a Porcine Intracerebral Hemorrhage Model Markedly Decreases Proinflammatory Cytokine Gene Expression in Perihematomal White Matter 
Kenneth R Wagner, Shauna Beiler, Christian Beiler, Michael J Linke, Gabrielle M de Courten-Myers, Univ of Cincinnati College of Med, Cincinnati, OH 
17 Safety Profile of Recombinant Factor VIIa in Patients with Intracerebral Haemorrhage 
Michael N Diringer, Washington Univ School of Med, St Louis, MO; Daniel Selchen, Trillum Health Ctr, Mississauga, ON, Canada; Stephen Davis, Royal Melbourne Hosp, Parkville, Australia; Stephan A Mayer, Columbia Univ College of Physicians and Surgeons, New York, NY; Nikolai C Brun, Novo Nordisk A/S, Copenhagen, Denmark; Joseph Broderick, Univ of Cincinnati Med Ctr, Cincinnati, OH; Brett E Skolnick, Novo Nordisk Inc, Princeton, NJ; Thorsten Steiner, Univ of Heidelberg, Heidelberg, Germany; Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators 
18 Myocardial Injury in Patients with Intracerebral Hemorrhage Treated with Recombinant Factor VIIa 
Rebecca M Sugg, Nicole R Gonzales, Dawn E Matherne, Marc Ribo, Hashem M Shaltoni, Elizabeth A Noser, John Y Choi, Andrei V Alexandrov, James C Grotta, The Univ of Texas--Houston Med School, Houston, TX 
19 Neuroprotection by Intravenous Human Neural Stem Cell Transplantation in Intracerebral Hemorrhage with Anti-inflammatory and Anti-apoptotic Effects 
Kon Chu, Manho Kim, Keun-Hwa Jung, Soon-Tae Lee, Dong-In Sinn, Jeong-Min Kim, Song-Yi Ko, Stroke and Neural Stem Cell Lab, Seoul National Univ Hosp, Seoul, Republic of Korea; Seung U Kim, Brain Disease Res Ctr, Ajou Univ, Suwon, Republic of Korea; Jae-Kyu Roh, Stroke and Neural Stem Cell Lab, Seoul National Univ Hosp, Seoul, Republic of Korea 
20 A Tool for Predicting Outcome After Spontaneous Supratentorial Intracerebral Haemorrhage 
Barbara A Gregson, A David Mendelow, Univ of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom; STICH Investigators 
21 New York Islands AVM Study: 5-Year AVM Detection Rates and Age-Dependent Incidence of AVM Hemorrhage 
C Stapf, C Hofmeister, J H Choi, H Mast, J P Mohr, Stroke Ctr, Columbia Univ, New York, NY; for the New York Islands AVM Study Collaborators 
Discussion
2:00-3:30 p.m. Session IV:  Concurrent D
In-hospital Treatment Oral Abstracts
Moderators: Laszlo Csiba, Debrecen, Hungary
Antonio Carolei, Rome, Italy
22 Stent-Assisted Angioplasty in Ostium of Vertebral Artery 
Bin Du, Ning Ma, Wei-Jian Jiang, Beijing Tiantan Hosp, Beijing, China 
23 Get With The Guidelines--Stroke Produces Sustainable Improvements in Hospital-Based Acute Stroke Care 
Lee H Schwamm, Massachusetts General Hosp, Boston, MA; Kenneth A LaBresh, MassPRO, Waltham, MA; Wenqin Pan, Duke Clinical Res Inst, Durham, NC; Michael Frankel, Emory Univ School of Med, Atlanta, GA; on behalf of the GWTG Steering Committee and Investigators 
24 Safety and Feasibility of Intra-arterial Autologous Bone Marrow Mononuclear Cell Transplantation in Acute Ischemic Stroke 
Gabriel R de Freitas, Univ Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Maria Lúcia F Mendonça, Daniel C Bezerra, Suzana A Silva, Carlos Henrique Falcão, Constantino S Gonzales, Rodrigo C Moreira, Andrea F Haddad, Fabio A Tuche, Pró-Cardíaco Hosp, Rio de Janeiro, Brazil; Daniel P Santos, Charles Andre, Univ Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Claudio T Mesquita, Amarino A Oliveira, Pró-Cardíaco Hosp, Rio de Janeiro, Brazil; Vinicio Elia, Hosp Municipal Miguel Couto, Rio de Janeiro, Brazil; Hans J Dohmann, Pró-Cardíaco Hosp, Rio de Janeiro, Brazil; Radovan Borojevic, Rosália Mendez-Otero, Univ Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Hans Dohmann, Pró-Cardíaco Hosp, Rio de Janeiro, Brazil
25 Intracranial Stent-Assisted Angioplasty in Symptomatic Intracranial Stenosis 
Wei-Jian Jiang, Thomas W Leung, Xiao-Tong Xu, Bin Du, Yong-Jun Wang, Beijing Tiantan Hosp, Beijing, China 
26 Prognostic Value of Glucose Levels in Acute Stroke Outcome: GLIA Study 
Blanca Fuentes, Exuperio Díez-Tejedor, Hosp Univ La Paz, Madrid, Spain; José Castillo, Hosp Clínico Univ, Santiago de Compostela, Spain; Antonio Dávalos, Hosp Can Ruti, Badalona, Spain; Antonio Gil Nuñez, Hosp Univ Gregorio Marañon, Madrid, Spain; José Vivancos, Hosp Univ La Princesa, Madrid, Spain; José Egido, Hosp Clínico Univ San Carlos, Madrid, Spain; on Behalf of the Stroke Project. Cerebrovascular Diseases Study Group. Spanish Society of Neurology 
27 Influence of Statin Withdrawal on Acute Ischemic Stroke Outcome: A Randomized Prospective Study 
Florentino Nombela, Hosp Univ de la Princesa, Madrid, Spain; Miguel Blanco, Hosp Clínico Univ, Santiago de Compostela, Spain; M A Moro, School of Med, Univ Complutense, Madrid, Spain; Manuel Rodríguez-Yáñez, Rogelio Leira, Hosp Clínico Univ, Santiago de Compostela, Spain; Ignacio Lizasoain, School of Med, Univ Complutense, Madrid, Spain; Mónica Millán, Hosp Germans Trias i Pujol, Badalona, Spain; Joaquin Serena, Hosp Dr Josep Trueta, Girona, Spain; Jose Vivancos Mora, Hosp Univ de la Princesa, Madrid, Spain; Jose Castillo, Hosp Clínico Univ, Santiago de Compostela, Spain 
28 Use of Lipid-Lowering Agents During Acute Ischemic Stroke Decreases In-Hospital Mortality 
Norrina B Allen, Lawrence M Brass, Yale Univ, New Haven, CT; Julie Cerese, Jackie Dostal, Joanne Cuny, Univ HealthSystem Consortium, Oak Brook, IL; Judith H Lichtman, Yale Univ, New Haven, CT
Discussion
3:30-4:00 p.m. Exhibits/Break
4:00-5:30 p.m. Session V:  Concurrent Symposia A
Ischemic Stroke Genetics in 2006
Moderators: James F. Meschia, Jacksonville, Florida
Jonathan Rosand, Boston, Massachusetts
From Genetics to Therapeutics
Stephen S. Rich, Winston-Salem, North Carolina
Smoking, Genetics, and Stroke:  The Smoking Gun
John Cole, Baltimore, Maryland
Monogenic Stroke in Clinical Practice
Martin Dichgans, Munchen, Germany
Decoding the Relevance of PDE4D for Stroke Risk and Potential Therapeutics
Bradford B. Worrall, Charlottesville, Virginia
Update on SWISS and ISGS
James F. Meschia, Jacksonville, Florida
Discussion
4:00-5:30 p.m. Session V:  Concurrent Symposia B
Poststroke Depression Research in Survivors and Caregivers
Moderators: Cheryl E. Weber, Rochester, New York
Joanne H. Evans, Salem, Massachusetts
Stroke Survivor's Poststroke Depression
Julien Bogousslavsky, Lausanne, Switzerland
Caregiver's Depression
Anu Berg, Lappeenranta, Finland
Interventions for Poststroke Depression Focused on Stroke Survivors
Linda S. Williams, Indianapolis, Indiana
Interventions for Stroke Caregiver Depression
Rosemarie B. King, Chicago, Illinois
Discussion
4:00-5:30 p.m. Session V:  Concurrent C
Outcomes Oral Abstracts Presentations I:  Clinical Epidemiology 
Moderators: Irene Katzan, Cleveland, Ohio
Cheryl Bushnell, Durham, North Carolina 
29 Lipoprotein-Associated Phospholipase A2 and C-Reactive Protein as Predictors of Stroke Recurrence and Death: The Northern Manhattan Study 
Mitchell S Elkind, Kristen Coates, Wanling Tai, Ralph L Sacco, Columbia Univ, New York, NY 
30 Elevated White Blood Cell Count and Increased Risk for Stroke and Vascular Death in Patients with Symptomatic Intracranial Disease 
Bruce Ovbiagele, UCLA School of Med, Los Angeles, CA; Michael J Lynn, Emory Univ School of Public Health, Atlanta, GA; Jeffrey L Saver, UCLA School of Med, Los Angeles, CA; Marc I Chimowitz, Emory Univ School of Med, Atlanta, GA; for the WASID Study Group 
31 Hemorrhagic Transformation Is Associated with Hyperthermia in Patients with Acute Stroke 
Rogelio Leira, Hosp Clínico Univ, Santiago de Compostela, Spain; Mar Castellanos, Hosp Dr Josep Trueta, Girona, Spain; Javier Arenillas, Hosp Germans Trias i Pujol, Badalona, Spain; Florentino Nombela, Hosp de la Princesa, Madrid, Spain; Tomás Sobrino, Hosp Clínico Univ, Santiago de Compostela, Spain; Yolanda Silva, Hosp Dr Josep Trueta, Girona, Spain; Javier Abella, Hosp Clínico Univ, Santiago de Compostela, Spain; Salvador Pedraza, Hosp Dr Josep Trueta, Girona, Spain; María Ángeles Moro, Univ Complutense, Madrid, Spain; José Vivancos, Hosp de la Princesa, Madrid, Spain; Joaquín Serena, Hosp Dr Josep Trueta, Girona, Spain; Antonio Dávalos, Hosp Germans Trias i Pujol, Badalona, Spain; José Castillo, Hosp Clínico Univ, Santiago de Compostela, Spain 
32 Antiplatelet Use Is Associated with Less Severe Stroke in Patients with No Prior History of Stroke or TIA 
Nerses Sanossian, Jeffrey L Saver, Tannaz Razinia, Doojin Kim, Bruce Ovbiagele, UCLA, Los Angeles, CA 
33 Trends in 30-Day and Long-Term Survival After First-Ever Ischemic Stroke: The Greater Cincinnati/Northern Kentucky Stroke Study, 1993-1994 vs 1999 
Yong-Jin Cho, Ilsan Paik Hosp, Inje Univ, Goyang, Republic of Korea; Dawn Kleindorfer, Jane C Khoury, Charles J Moomaw, Kathleen Alwell, Daniel Woo, Matthew L Flaherty, Pooja Khatri, Joseph P Broderick, Brett M Kissela, Univ of Cincinnati College of Med, Cincinnati, OH 
34 An Improved Prediction Model for Acute Ischemic Stroke 
Karen C Johnston, Douglas P Wagner, Univ of Virginia, Charlottesville, VA; George C Newman, Univ of Wisconsin, Madison, WI; Vincent Thijs, Univ Hosp Leuven, Leuven, Belgium; Souvik Sen, Univ of North Carolina, Chapel Hill, NC; Steven Warach, NIH-NINDS, Bethesda, MD; for the GAIN and Citicoline Investigators 
35 Cross-Validation of a Simple 3-Point Prediction Rule to Stratify 7-Day Stroke Risk After TIA 
S Claiborne Johnston, UCSF Med Ctr, San Francisco, CA; Peter M Rothwell, Stroke Prevention Research Unit, Univ of Oxford, Oxford, United Kingdom; Mai Nguyen-Huynh, UCSF Med Ctr, San Francisco, CA; Matthew Giles, Stroke Prevention Research Unit, Univ of Oxford, Oxford, United Kingdom; Jacob S Elkins, UCSF Med Ctr, San Francisco, CA; Stephen Sidney, Kaiser-Permanente Med Care Plan, Oakland, CA 
Discussion
4:00-5:30 p.m. Session V:  Concurrent D
Pathophysiology/Thrombosis Oral Abstracts
Moderators: Gary A Rosenberg, Albuquerque, New Mexico
Jin-Moo Lee, St. Louis, Missouri
36 Synergistic Effects of Statins and Dipyridamole on Stroke Protection: Mechanisms Beyond Lipid Lowering and Platelet Inhibition 
Hyung-Hwan Kim, Brigham and Women's Hosp, Boston, MA; Zhipeng Zhou, Michael A Moskowitz, Massachusetts General Hosp, Boston, MA; James K Liao, Brigham and Women's Hosp, Boston, MA 
37 C-Reactive Protein Induced Disruption of the Blood Brain Barrier Is Prevented by Statins: Involvement of Oxidative Stress, Endothelial Contractile Machinery, and Nitric Oxide 
Christoph R Kuhlmann, Heiko J Luhmann, Inst of Physiology, Johannes Gutenberg Univ, Mainz, Germany 
38 Elevated Matrix Metalloproteinase-9 Associated with Transient Ischemic Attack, Stroke, or Death in Patients with Carotid Stenosis 
Nikolaj Eldrup, Marie-Louise Grønholdt, Henrik Sillesen, Rigshospitalet, Copenhagen, Denmark; Børge Nordestgaard, Herlev Univ Hosp, Herlev, Denmark
39 Phosphodiesterase 4 as Regulator of Brain Infarction and Brain Endothelial Fibrinolysis 
Dong Xue, Fan Yang, Shur-Jen Wang, Jeong Kim, Steven Schreiber, Mark Fisher, UCI, Irvine, CA 
40 Variations in Blood-Brain Barrier Opening in Stroke Demonstrated by Magnetic Resonance Imaging with Contrast Agents of 2 Different Sizes 
Tavarekere N Nagaraja, Richard L Croxen, Polly A Whitton, Kelly A Keenan, Joseph D Fenstermacher, Robert A Knight, Henry Ford Health System, Detroit, MI 
41 Plasminogen Activator Inhibitor Type-1 Expression in Vascular Smooth Muscle and Microvascular Endothelial Cells Is pp60c-src/Mitogen-Activated Kinase/Upstream Stimulatory Factor Dependent and a Potential Target for Stroke Therapy 
Paul J Higgins, Albany Med College, Albany, NY 
42 3-Dimensional High-Resolution Magnetic Resonance Direct Thrombus Imaging: Detection of Carotid AHA Type VIb/c Plaque 
Richard Bitar, Univ of Toronto, Sunnybrook and Women's College HSC, Toronto, ON, Canada; General Leung, Susan Crisp, Sunnybrook and Women's College HSC, Toronto, ON, Canada; Sean Symons, Univ of Toronto, Sunnybrook and Women's College HSC, Toronto, ON, Canada; Corwyn Rowsell, Univ of Toronto, Toronto, ON, Canada; Jagdish Butany, Univ of Toronto, Univ Health Network, Toronto, ON, Canada; David Gladstone, D James Sahlas, Regional Stroke Ctr, Sunnybrook and Women’s College HSC, Toronto, ON, Canada; Alexander Kiss, Inst for Clinical Evaluative Sciences, Toronto, ON, Canada; Andrew Nelson, Sunnybrook and Women's College HSC, Toronto, ON, Canada; Robert Maggisano, Sunnybrook and Women’s College HSC, Toronto, ON, Canada; Alan R Moody, Univ of Toronto, Sunnybrook and Women's College HSC, Toronto, ON, Canada 
Discussion
5:30-7:30 p.m. Poster Session I/Reception