American Heart Association

Please note: Seating is on a first-come, first-served basis. According to fire code, a session must and will be closed if the room is filled to capacity.

International Attendees
On Wednesday, international attendees can mingle with Stroke Council leaders during the Poster Session I Reception. The informal gathering will be held at the back of the Poster Hall on the right in the tabled area.

7:30 a.m. - 9 a.m.

Session I: Concurrent Symposia A
How to Make Stroke Models Matter
Room RO-2

Moderators: Thaddeus Nowak, Ph.D., Memphis, Tenn.
David Howells, Ph.D., Melbourne, Australia

7:30 Quality Control for Modeling
Ulrich Dirnagl, Berlin, Germany

7:45 From In Vitro to In Vivo: Models of Cerebral Ischemia
Miguel A. Perez-Pinzon, Ph.D., Miami, Fla.

8:00 Role of Gender in Animal and Cell Models of Stroke
Patricia D. Hurn, Ph.D., FAHA, Portland, Ore.

8:15 Physiologic Control and Hyperglycemia in Stroke Models
Thomas A. Kent, M.D., FAHA, Houston, Texas

8:30 Genes, Species and Translation
Richard J. Traystman, Ph.D., FAHA, Denver, Colo.

8:45 Discussion

Session I: Concurrent Symposia B
Intracranial Aneurysms: Current State-of-the-Art
Room RO-6
This session has been jointly organized by the American Stroke Association, AANS/CNS Cerebrovascular Section and the Society of NeuroInterventional Surgery.

Moderators: Charles (Mike) Cawley, M.D., Atlanta, Ga.
Joshua A. Hirsch, Boston, Mass.

7:30 Microsurgery - The Refinement of Surgical Adjuncts
Arthur L. Day, M.D., Boston, Mass.

7:50 Endovascular Frontiers: What's Next?
Michael Mawad, Houston, Texas

8:10 Real Life: How Do We Choose? Microsurgery vs Endovascular (Debate)
Frederic Meyer, M.D., Rochester, Minn.
Juha Hernesniemi, M.D., PhD, Helsinki, Finland

8:50 Discussion

Session I: Concurrent Symposia C
Clinical Approaches to Brain Repair after Stroke
Hall B 2-2

Moderators: Steven C. Cramer, M.D., Orange, Calif.
Sean I Savitz, M.D., FAHA, Houston, Texas

7:30 Modulating Specific Neurotransmitter Systems
Steven C. Cramer, M.D., Orange, Calif.

7:50 Task-Oriented Training
Carolee J. Winstein, Ph.D., P.T., FAPTA, Los Angeles, Calif.

8:10 Electromagnetic Brain Stimulation
Leonardo Cohen, M.D., Bethesda, Md.

8:30 Cellullar Therapies
Sean I. Savitz, M.D., FAHA, Houston, Texas

8:50 Discussion

Session I: Concurrent Symposia D
Cognitive Implications of "Mixed" Cerebrovascular and Alzheimer's Disease
Room La Louisianne C

Moderators: Sandra Black, M.D., FAHA, Toronto, Canada
David Nyenhuis, Ph.D., Chicago, Ill.

7:30 Interactions between Cerebral Ischemia and Beta-amyloid Toxicity in a Rodent Model: Implications for "Mixed" AD and CVD
David F. Cechetto, Ph.D., London, Ontario, Canada

7:50 Voxel-based Morphometric Differences between Patients with Amnestic MCI and Vascular CIND
Glenn T. Stebbins, Ph.D., Chicago, Ill.

8:10 The Epidemiology of Mixed AD and Cerebrovascular Disease
David Nyenhuis, Ph.D., Chicago, Ill.

8:30 Treatment Options for Patients with Mixed AD and Cerebrovascular Disease
Sandra Black, M.D., FAHA, Toronto, Canada

8:50 Discussion

Session I: Concurrent E
Oral Abstract Presentations: Hemorrhage - Intraparenchymal
Room La Louisianne A/B

Moderator: Mark P. Goldberg, St. Louis, Mo.

7:30 Subgroup Analysis In the Fast Trial: A Subset of Intracerebral Hemorrhage Patients That Benefit from Recombinant Activated Factor VII? 1
Stephan A. Mayer, Columbia Univ, New York, N.Y.; Stephen M. Davis, University of Melbourne, Melbourne, Australia; Kamilla Begtrup, Novo Nordisk A/S, Copenhagen, Denmark; Joseph P. Broderick, University of Cincinnati, Cincinnati, Ohio; Michael N. Diringer, Washington University, St. Louis, Mo.; Brett E. Skolnick, Novo Nordisk, Inc., Princeton, N.J.; Thorsten Steiner, University of Heidelberg, Heidelberg, Germany

7:42 Microbleeds Versus Macrobleeds: Evidence for Distinct Processes 2
Steven M. Greenberg, R. N. Kaveer Nandigam, David Schoenfeld, Hui Zhang, Massachusetts General Hospital, Boston, Mass.; Rebecca A. Betensky, Harvard School of Public Health, Boston, Mass.; Jonathan Rosand, Anand Viswanathan, Eric E. Smith, Massachusetts General Hosp, Boston, Mass.

7:54 Multicentre Prospective Study Demonstrates Feasibility Of CT-Angiography In Intracerebral Hemorrhage And Validity Of "Spot Sign" For Hematoma Expansion Prediction 3
Andrew M. Demchuk, Suresh Subramaniam, Jayme Kosior, Sarah Tymchuk, Christine O'Reilly, University of Calgary, Calgary, AB, Canada; Carlos Molina, Vall d'Hebron Hosp, Barcelona, Spain; Jayanta Roy, Advance Medicare and Research Institute, Kolkata, India; Imanuel Dzialowski, University of Dresden, Dresden, Germany; Jean-Martin Boulanger, Univ of Sherbrooke, Greenfield Park, QC, Canada; Mohammed Alzawahmah, Nic Weir, Michael D. Hill, University of Calgary, Calgary, AB, Canada; David Gladstone, Richard Aviv, University of Toronto -Sunnybrook Health Sciences Center, Toronto, ON, Canada; PREDICT/Sunnybrook ICH CTA Study Group

8:06 Polymorphisms in the Aquaporin 4 and Thrombin protease-activated receptors gene are related to Edema Volume In Patients With Acute Intracerebral Hemorrhage 4
Yolanda Silva, Sebastian Remollo, Judith Mallolas, Hospital, Dr. Josep of Girona, Girona, Spain; Natalia Pérez de la Ossa, Hosp Germans Trias i Pujol, Badalona, Spain; Mar Castellanos, Verónica Cruz, Hospital, Dr. Josep of Girona, Girona, Spain; Florentino Nombela, Hosp de la Princesa, Madrid, Spain; José Castillo, Hosp Clínico Univrio, Santiago de Compostela, Spain; Joaquín Serena, Hosp Dr Josep of Girona, Girona, Spain

8:18 Antiplatelet Medications and Hemorrhage Growth After Intracerebral Hemorrhage 5
Lauren H. Sansing, Steven R. Messe, Brett L. Cucchiara, University of Pennsylvania, Philadelphia, Pa.; Stanley N. Cohen, University of Nevada, Las Vegas, Nev.; Patrick D. Lyden, University of California-San Diego, San Diego, Calif.; Scott E. Kasner, University of Pennsylvania, Philadelphia, Pa.; for the CHANT Investigators

8:30 In Vivo 11C PIB Binding is Increased in Patients with Cerebral Amyloid Angiopathy Haemorrhage 7
John V. Ly, Geoffrey A. Donnan, National Stroke Research Institute, Heidelberg Heights, Australia; Victor L Villemagne, Department of Nuclear Medicine, Center for PET, Austin Health, Heidelberg, Australia, Heidelberg, Australia; Jorge A. Zavala, Henry Ma, National Stroke Research Institute, Heidelberg Heights, Australia; Graeme O'Keefe, Uwe Ackerman, Henri Tochon-Danguy, Christopher C. Rowe, Department of Nuclear Medicine, Center for PET, Austin Health, Heidelberg, Australia

8:42 Discussion

9 a.m. - 9:10 a.m.
Short Break

9:10 a.m. - 10:40 a.m.

Session II: Concurrent Symposia A
Giant Intracranial Aneurysm: A Difficult Challenge
Room RO-6
This session has been jointly organized by the American Stroke Association, AANS/CNS Cerebrovascular Section and the Society of NeuroInterventional Surgery.

Moderators: Sean Lavine, M.D., New York, N.Y.
Mary E. Jensen, M.D., Charlottesville, Va.

9:10 Microsurgery: Bypass and Other Adjuncts
Robert A Solomon, M.D., FAHA, New York, N.Y.

9:30 Endovascular Approaches
Jacques Moret, M.D., Paris, France

9:50 Real Life: How Do We Choose? Microsurgery vs Endovascular (Debate)
Daniel Barrow, M.D., FAHA, Atlanta, Ga.
Sean Lavine, M.D., New York, N.Y.

10:30 Discussion

Session II: Concurrent Symposia B
Stroke in Sickle Cell Disease: Recent Successes and On-going Challenges
Hall B 2-2

Moderators: Robert J Adams, M.D., M.S., FAHA, Charleston, S.C.
Fenella J. Kirkham, London, United Kingdom

9:10 Changing Demographics of Stroke in Sickle Cell Disease
Heather J. Fullerton, M.D., San Francisco, Calif.

9:30 The STOP Trials: Lessons Learned and On-going Challenges
Robert J. Adams, M.D., M.S., FAHA, Charleston, S.C.

9:50 Small Vessel Stroke in Sickle Cell Disease: the Next Big Challenge
Michael DeBaun, St. Louis, Mo.

10:10 Genetic Predictors of Stroke in Sickle Cell Disease: How Can they Help Us?
James F. Meschia, M.D., FAHA, Jacksonville, Fla.

10:30 Discussion

Session II: Concurrent C
Oral Abstract Presentations: Outcomes
Room La Louisianne C

Moderators: Larry B Goldstein, M.D., FAAN, FAHA, Durham, N.C.
Karen C. Johnston, M.D., M.S., FAHA, Charlottesville, Va.

9:10 Long-Term Prognosis After Transient Ischemic Attack (TIA) 8
Anthony S. Kim, UCSF, San Francisco, Calif.; Stephen Sidney, Division of Res Kaiser Permanente Northern California, Oakland, Calif.; Allan L. Bernstein, Kaiser Santa Rosa Medical Center, Santa Rosa, Calif.; S. Claiborne Johnston, UCSF, San Francisco, Calif.

9:22 Low-Income, Low-hospital Volume And High Stroke Mortality: The Puzzling Route Of Inequity 9
Gustavo Saposnik, University of Toronto, Toronto, ON, Canada; Thomas Jeerakathil, Univ of Alberta, Edmonton, AB, Canada; Daniel Selchen, University of Toronto, Missassauga, ON, Canada; Vladimir Hachinski, University of Western Ontario, London, ON, Canada; Moira K. Kapral, University of Toronto, Toronto, ON, Canada; on behalf of the Stroke Outcome Research Canada (SORCan) Working Group

9:34 Does Stroke Patient's Weight Influence The Response To Intravenous t-PA? 10
Min Lou, The 2nd Affiliated Hospital of Zhejiang University, Hangzhou, China; Magdy H Selim, Beth Israel Deaconess Medical Center, Boston, Mass.

9:46 Chronic Kidney Disease is a Strong Independent Predictor of Poor Outcome in Patients With Acute Stroke 11
Gilad Yahalom, Roseline Schwartz, Yvonne Schwammenthal, Oleg Merzeliak, Maya Toashi, David Orion, David Tanne, Chaim Sheba Medical Ctr, Tel-Hashomer, Israel

9:58 The Impact of Case Managed Care in Patients with Acute Stroke and Transient Ischemic Attack 12
Annette C. Robertson, Jiming Fang, Inst for Clinical Evaluative Sciences, Toronto, ON, Canada; M. Patrice Lindsay, Canadian Stroke Network, Ottawa, ON, Canada; Moira K. Kapral, Frank L. Silver, University of Toronto, Toronto, ON, Canada

10:10 Long-term Use of Secondary Stroke Prevention Therapies among US Veterans 13
Deborah A. Levine, Monika M. Safford, Jeroan J. Allison, Thomas K. Houston, University of Alabama Birmingham, Birmingham, Ala.; Dean M. Reker, Kansas VA Medical Center, Kansas City, Mo.; Peter H. King, Birmingham VA Medical Center, Birmingham, Ala.; Linda S. Williams, Roudebush VA Medical Center, Indianapolis, Ind.; Mark S. Litaker, Catarina I. Kiefe, University of Alabama Birmingham, Birmingham, Ala.

10:22 Randomized Controlled Trial of a Post-stroke Post-discharge Care Management Intervention 14
Kyle R. Allen, Susan Hazelett, Summa Health System, Akron, Ohio; Dave Jarjoura, Ohio State University, Columbus, Ohio; Kathy Wright, Janice Weinhardt, Summa Health System, Akron, Ohio

10:34 Discussion

Session II: Concurrent D
Oral Abstract Presentations: Acute Management I
Room La Louisianne A/B

Moderators: Stephen M. Davis, M.D., Parkville, Australia
Devin L. Brown, M.D., FAHA, Ann Arbor, Mich.

9:10 The Combined Approach To Lysis Utilizing Eptifibatide And rt-PA In Acute Ischemic Stroke (the CLEAR Stroke Trial): Final Results From Tier I and II 15
Arthur M. Pancioli, University of Cincinnati, Cincinnati, Ohio; for the CLEAR Trial Investigators

9:22 Does Study Enrollment Delay Treatment with Intravenous Thrombolytics for Acute Ischemic Stroke? 16
Sheryl Martin Schild, UT Houston Health Science Center, Houston, Texas; Karen C. Albright, UCSD, San Diego, Calif.; Hen Hallevi, Andrew D. Barreto, Nicole R. Gonzales, UT Houston Health Science Center, Houston, Texas; Aslam M. Khaja, University of Illinois at Chicago, Chicago, Ill.; Kachi Illoh, Elizabeth A. Noser, James C. Grotta, Sean I. Savitz, UT Houston Health Science Center, Houston, Texas

9:34 Lack of Adherence to Guidelines for Pre-TPA Blood Pressure Levels Is Associated with Higher Risk of Symptomatic Intracerebral Hemorrhage 17
Georgios Tsivgoulis, Stroke Program, Barrow Neurological Institute, Phoenix Ariz., and UAB Comprehensive Stroke Center, Birmingham, Ala.; James L. Frey, Stroke Program, Barrow Neurological Institute, Phoenix, Ariz.; Vijay K. Sharma, Division of Neurology, Department of Medicine, Nattional University Hospital, Singapore, Singapore; Annabelle Y. Lao, Steven L. Hoover, Wei Liu, Murray Flaster, Stroke Program, Barrow Neurological Institute, Phoenix, Ariz.; Anne W. Alexandrov, Comprehensive Stroke Center, University of Alabama at Birmingham Hospital, Birmingham, Ala.; Marc Malkoff, Stroke Program, Barrow Neurological Institute, Phoenix, Ariz.; Andrei V. Alexandrov, Comprehensive Stroke Center, University of Alabama at Birmingham Hospital, Birmingham, Ala.

9:46 Feasibility of Caffeinol and Hypothermia for Acute Ischemic Stroke 18
Sheryl Martin-Schild, Andrew D. Barreto, Hen Hallevi, UT Houston Health Science Center, Houston, Texas; Aslam M. Khaja, University of Illinois at Chicago, Chicago, Ill.; Hashem Shaltoni, Nicole R. Gonzales, Kachi Illoh, Elizabeth A. Noser, Jarek Aronowski, Sean I. Savitz, James C. Grotta, UT Houston Health Science Ctr, Houston, Texas

9:58 The Metabolic Syndrome is Associated with a Higher Resistance to i.v. Thrombolysis for Acute Ischemic Stroke in Women Than in Men 19
Juan F Arenillas, Patricio Sandoval, Natalia Pérez de la Ossa, Mónica Millán, Cristina Guerrero, Domingo Escudero, Laura Dorado, Elena López-Cancio, Ana C. Ricciardi, Neurosciences Dep. Germans Trias i Pujol Univry Hosp, Barcelona, Spain; José Castillo, Neurosciences Dep. General Univry Hosp, Santiago de Compostela, Spain; Antoni Dávalos, Neurosciences Dep. Germans Trias i Pujol Univry Hosp, Barcelona, Spain

10:10 A Method to Predict Stroke Trial Success Based on Pooled Control Arms 20
Pitchaiah Mandava, Thomas A. Kent, MEDVAMC/BCM, Houston, Texas

10:22 Influence Of Polymorphisms Of F12 46 C/t, F7 670 A/c And F7 401/-323 On The Outcome And The Risk Of Cerebral Hemorrhage In Patients With Ischemic Stroke Treated With Rt-pa 21
Joan Martí-Fàbregas, Dolores Cocho, José Manuel Soria, Hosp de la Santa Creu i Sant Pa, Barcelona, Spain; Joan Montaner, Hosp Vall d'Hebron, Barcelona, Spain; Isabel Tirado, Hosp de la Santa Creu i Sant Pa, Barcelona, Spain; Israel Fernández-Cadenas, Hosp Vall d'Hebron, Barcelona, Spain; Sergi Martínez-Ramírez, Eugenia Martínez-Hernández, Daniel Alcolea, Marta Marquié, Jordi Fontcuberta, Josep-Lluis Martí-Vilalta, Hosp de la Santa Creu i Sant Pa, Barcelona, Spain

10:34 Discussion

Session II: Concurrent E
Oral Abstract Presentations: Experimental Ischemia I
Room RO-2

Moderators: Miguel A Perez-Pinzon, PhD, Miami, Fla.
Nabil J. Alkayed, M.D., PhD, Portland, Ore.

9:10 Selective ETA Receptor Antagonism: Perfusion/Diffusion MRI Defines Treatment Efficacy, Mechanism and Translatable Stroke Model for SB 234551 22
Frank C. Barone, Stephen C Lenhard, Robin E. Haimbach, Thomas R. Schaeffer, Ross G. Bentley, Matthew J McVey, Sudeep Chandra, Elaine A. Irving, Andrew A. Parsons, Jeffrey J Legos, GlaxoSmithKline, King Of Prussia, Pa.

9:22 NADPH Oxidase from Circulating Inflammatory Cells Exacerbates Injury in Experimental Stroke 23
Xian Nan Tang, UCSF & SF VAMC, Stanford University, San Francisco, Calif.; Zhen Zheng, UCSF & SF VAMC, San Francisco, Calif.; Nick Cairns, Combinix, Inc., Mountain View, Calif.; Belinda Cairns, Combinix, Inc, Mountain View, Calif.; Rona G. Giffard, Stanford University, Stanford, Calif.; Midori A. Yenari, UCSF & SF VAMC, San Francisco, Calif.

9:34 Mast Cells Are Early Responders After Hypoxia-ischemia In Immature Rat Brain 24
Yuxuan Jin, Susan J Vannucci, Ann-Judith Silverman, Columbia Univ Medical Ctr, New York, N.Y.

9:46 Key Role of the Scavenger Receptor CD36 in Postischemic Inflammation and Ischemic Brain Injury 25
Alexander Kunz, Dept. of Neurology, University Hospital, Dresden, Germany; Takato Abe, Karin Hochrainer, Josef Anrather, Gianfranco Racchumi, Ping Zhou, Costantino Iadecola, Division of Neurobiology, Weill Cornell Medical Coll, New York, N.Y.

9:58 Effects Of Hypothermia On Focal Cerebral Ischemia In Plasminogen Knockout Mice 26
Jan Burk, Dorothe Burggraf, Ludwig-Maximilians University - Department of Neurology, Munich, Germany; Milan Vosko, AKh Linz, Linz, Austria; Martin Dichgans, Ludwig-Maximilians University - Department of eurology, Munich, Germany; Gerhard F. Hamann, HSK Dr. Horst-Schmidt-Klinik - Department of Neurology, Wiesbaden, Germany

10:10 Timing Of MGE Cell Transplantation After Distal Middle Cerebral Artery Occlusion Significantly Influences The Cell-host Interaction 27
Hideo Shichinohe, Marcel M. Daadi, Nobutaka Horie, Theo D. Palmer, Tonya Bliss, Gary K. Steinberg, Stanford University, Stanford, Calif.

10:22 Resveratrol Preconditioning Induced Neuroprotection Is Mediated Via Sirt1-Uncoupling Protein 2 Pathway. 28
David Della Morte, Kunjan R. Dave, Miguel A Perez-Pinzon, University of Miami, Miami, Fla.

10:34 Discussion

10:40 - 11:10 a.m.
Exhibits/Break
Hall A

11:10 a.m. - 12:45 p.m.

Session III: Plenary Session I
Hall B 2

Moderators: Philip B. Gorelick, M.D., M.P.H., FACP, Chicago, Ill.
Patricia D. Hurn, PhD, FAHA, Portland, Ore.

11:10 Conference Opening
Philip B. Gorelick, M.D., M.P.H., FACP, Chicago, Ill.

11:15 American Heart Association/American Stroke Association President's Remarks
Daniel W. Jones, M.D., FAHA, Jackson, Miss.

11:20 Introduction of the Thomas Willis Lecture
Philip B Gorelick, M.D., M.P.H., FACP, Chicago, Ill.

11:25 Thomas Willis Lecture
Reperfusion and Neurovascular Dysfunction in Stroke: From Basic Mechanisms to Potential Strategies for Neuroprotection
Pak H. Chan, Ph.D., FAHA, Stanford, Calif.

11:45 A Tribute to Dr. David Sherman, M.D., FAHA
J. Donald Easton, M.D., Providence, R.I.

Plenary Symposium
Blood to Save Brain: Endothelial Precursors, Stem Cells and Angiogenesis for Brain Repair

Moderators: Eng H Lo, Ph.D., Charlestown, Mass.
Zvonimir S Katusic, M.D., Ph.D., FAHA, Rochester, Minn.

11:55 Introduction
Eng H. Lo, Ph.D., Charlestown, Mass.

12:00 Circulating Endothelial Precursors and Therapeutic Angiogenesis
Zvonimir S. Katusic, M.D., Ph.D., FAHA, Rochester, Minn.

12:15 Integrated Responses in Neurovasculogenesis after Stroke
S. Thomas Carmichael, Jr., M.D., Los Angeles, Calif.

12:30 Functional or Dysfunctional Angiogenesis in Acute Stroke?
Partick Lyden, M.D., FAAN, San Diego, Calif.

12:45 - 2 p.m.
Exhibits and Lunch Break
Hall A

Nursing and Rehabilitation Professions Roundtable Luncheon (ticket required; seating is limited)
Room 208 - 210

Fellow and Early Career/Stroke Leader Luncheon (ticket required; seating is limited)
Room 220 - 222

2 - 3:30 pm

Session IV: Concurrent Symposia A
Reversing Ischemia and Restraining Hemorrhage: Vascular Endpoints in Acute Stroke Trials
Room La Louisianne A/B

Moderators: John R Marler, M.D., FAHA, Rockville, Md.
David S Liebeskind, M.D., FAHA,
Los Angeles, Calif.

2 Introduction
John R. Marler, M.D., FAHA, Rockville, Md.
David S. Liebeskind, M.D., FAHA, Los Angeles, Calif.

2:05 Recanalization, Reperfusion, Hemorrhage and Infarct Evolution
David S. Liebeskind, M.D., FAHA, Los Angeles, Cailf.

2:26 Angiographic Measures in Endovascular Thrombolysis and Thrombectomy Trials
Thomas Tomsick, M.D., Cincinnati, Ohio

2:47 Imaging and Clinical Outcomes in Stroke: Match or Mismatch?
Amie Hsia, M.D., FAHA, Washington, D.C.

3:08 Linking Surrogate and Clinical Outcomes From Early Hours to Day 90
Linda Williams, M.D., FAHA, Indianapolis, Ind.

Session IV: Concurrent Symposia B
Ovarian Hormones, Pregnancy and Stroke: Risks, Management and Prevention
Room La Louisianne C

Moderators: Barney J. Stern, M.D., Baltimore, Md.
Dilip K. Pandey, Ph.D., M.B.B.S., MS, Chicago, Ill.

2 Risks and Management of Ischemic Stroke During Pregnancy
Steven J Kittner, M.D., FAHA, Baltimore, Md.

2:20 Risks and Management Strategies for Vascular Anomalies During Pregnancy
Issam A Awad, M.D., M.Sc., FACS, MA, Evanston, Ill.

2:40 Preeclampsia/Eclampsia: Understanding the Pathophysiology of Cerebrovascular Complications
Cheryl Bushnell, M.D., M.H.S., FAHA, Winston-Salem, N.C.

3 Stroke and Ovarian Hormones: A Risky or Beneficial Relationship
Lousie D. McCullough, M.D., Farmington, Conn.

3:20 Discussion

Session IV: Concurrent Symposia C
Intracranial Occlusive Disease
Room RO-6
This session has been jointly organized by the American Stroke Association, AANS/CNS Cerebrovascular Section and the Society of NeuroInterventional Surgery.

Moderators: Felipe Albuquerque, M.D., Phoenix, Ariz.
Johnny C. Pryor, Boston, Mass.

2 Genetics and Natural History of Cerebrovascular Occlusive Disease
John P. Kane, M.D., FAHA, San Francisco, Calif.

2:20 Wingspan Stent Registry and Retrospective Data
Elad Levy, M.D., Buffalo, N.Y.

2:40 Proposed Intracranial Stent Trial Design
Peter Rasmussen, M.D., Cleveland, Ohio

3 Moya Moya
B. Gregory Thompson, Jr., M.D., Ann Arbor, Mich.

3:20 Discussion

Session IV: Concurrent Symposia D
Rehabilitation Intervention Effectiveness: Impact of Dose-response and Timing Post-stroke
Hall B 2-2

Moderators: Richard Macko, M.D., Baltimore, Md.
Julie Bernhardt, Ph.D., B.S.C., Melbourne, Australia

2 Dose Issues Related to the Specificity and Intensity of Rehabilitation Interventions: Evidence for Overtraining Effects
Katherine Sullivan, Ph.D., P.T., Los Angeles, Calif.

2:15 Dose Limits During the Acute Post-stroke Phase
Alexander Dromerick, M.D., FAHA, Washington, D.C.

2:30 Optimizing the Scheduling and Type of Exercise to Maximize Functional Outcomes
Carolynn Patten, Ph.D., P.T., Gainesville, Fla.

2:45 The Effect of Dose Monitoring Within a Clinical Trial
Julie Bernhardt, Ph.D., B.S.C., Melbourne, Australia

3 Discussion

Session IV: Concurrent E
Oral Abstract Presentations: Hemorrhage - Intracranial Aneurysm and Subarachnoid Hemorrhage
Room RO-2

Moderators: Charles (Mike) Cawley, M.D., Atlanta, Ga.
Elad I. Levy, M.D., Buffalo, N.Y.

2 Management of Unruptured Intracranial Aneurysm: Part 1 Natural History 29
Yuichi Murayama, Toshihiro Ishibashi, Takayuki Saguchi, Masaki Ebara, Hideki Arakawa, Koreaki Irie, Hiroyuki Takao, Toshiaki Abe, Jikei Univ, Tokyo, Japan

2:12 The Impact of Family History of Aneurysm or Subarachnoid Hemorrhage on Aneurysm Characteristics and Outcome: Results from the International Study of Unruptured Intracranial Aneurysms 30
Robert D. Brown Jr., Irene Meissner, John Huston III, David G. Piepgras, David O. Wiebers, Mayo Clinic, Rochester, Minn.; Joseph P. Broderick, Daniel Woo, University of Cincinnati, Cincinnati, Ohio; Elizabeth J. Cozzie, University of Iowa, Iowa City, Minn.; James C. Torner, University of Iowa, Iowa City, Iowa

2:24 Cost-effectiveness Analysis of Endovascular Treatment versus Neurosurgical Treatment for Ruptured Intracranial Aneurysms in the United States 31
Alberto Maud, M. Fareed K Suri, Kamakshi Lakshminarayan, Adnan I Qureshi, Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, Minn.

2:36 Long-term Follow-up Patients With Unruptured Intracranial Aneurysms 32
James C. Torner, University of Iowa, Iowa City, Iowa; Robert D. Brown Jr., Irene Meissner, David G. Piepgras, John Huston III, Jack Whisnant, David O. Wiebers, Mayo Clinic, Rochester, Minn.; International Study of Unruptured Intracranial Aneurysms Investigators

2:48 Under-Treatment and Outcomes of Non-Traumatic Subarachnoid Hemorrhage by Hospital Volume: A Multi-State Study 33
Lucas Elijovich, UCSF, San Francisco, Calif.; Nancy A. Dreyer, Outcome, Cambridge, Mass.; Jill Van Den Bos, Milliman, Denver, Colo.; S. Claiborne Johnston, UCSF, San Francisco, Calif.

3 Predictors of Retreatment of Ruptured Intracranial Aneurysms: The Cerebral Aneurysm Rupture After Treatment Study 34
Chirag G. Patil, Stanford University, Stanford, Calif.; Lucas Elijovich, University of California, San Francisco, San Francisco, Calif.; Gary K. Steinberg, Stanford University, Stanford, Calif.; Robert F. Spetzler, Cameron G. McDougall, Joseph M. Zabramski, Barrow Neurological Institure, Phoenix, Ariz.; Daryl R. Gress, Michael T. Lawton, Randall T. Higashida, University of California, San Francisco, San Francisco, Calif.; Gary R. Duckwiler, University of California, Los Angeles, Los Angeles, Calif.; Phillip D. Purdy, University of Texas, Southwestern, Dallas, Texas; David G. Piepgras, Mayo Clinic, Rochester, Minn.; Steven L. Giannotta, University of Southern California, Los Angeles, Calif.; S. Claiborne Johnston, University of California, San Francisco, San Francisco, Calif.

3:12 Unruptured Cerebral Aneurysms Presenting with Ischemic Events 35
Nancy McLaughlin, Michel W Bojanowski, CHUM - Hop Notre-Dame, Montreal, QC, Canada

3:24 Discussion

3:30 - 4 p.m.
Exhibits/Break
Hall A

4 - 5:30 p.m.

Session V: Concurrent Symposia A
Update on Cerebral Hemorrhage Trials
Room RO-6

Moderators: Michael Diringer, M.D., Ph.D., FAHA, Saint Louis, Mo.
Joseph P Broderick, M.D., FAHA, Cincinnati, Ohio

4 Acute Blood Pressure Management - The North American Perspective: Insights from the ATACH Trial
Adnan I Qureshi, M.D., FAHA, Minneapolis, Minn.

4:20 Acute Blood Pressure Management - The Australasian Perspective: Insights from the INTERACT Study
Craig Anderson, M.D., Ph.D., Sydney, NSW, Australia

4:40 Minimally Invasive Sterotactic Thrombolysis: A Report from the MISTIE Trial
Issam A Awad, M.D., M.Sc., FACS, MA, Evanston, Ill.

5:00 Intraventricular Hemorrhage: A Report from the CLEAR-IVH Trial
Daniel F. Hanley, M.D., Baltimore, Md.

5:20 Discussion

Session V: Concurrent Symposia B
New (and Some Old) Targets for Acute Intervention: From Science to the Clinic
Room La Louisianne C

Moderators: John Hallenbeck, M.D., Bethesda, Md.
Gregory J. del Zoppo, M.D., M.S., FAHA, Seattle, Wash.

4:00 Immunomodulation and the Reduction of Injury Volume
John Hallenbeck, M.D., Bethesda, Md.

4:20 Foundation for Intra-arterial Stroke Therapy Using Plasmin, a Direct-acting Thrombolytic Agent
Victor J Marder, M.D., Los Angeles, Calif.

4:40 Activated Protein C (APC): Modelling Stroke
Berislav V Zlokovic, M.D., Ph.D., Rochester, N.Y.

5 Modulating Endothelial Cell Anticoagulant Properties: Clinic Trials in Waiting
Mark Fisher, M.D., FAHA, Irvine, Calif.

5:20 Discussion

Session V: Concurrent Symposia C
Interactive Stroke Research
Room La Louisianne A/B

Moderators: Vladimir Hachinski, M.D., FAHA, London, Ontario, Canada
Constantino Iadecola, M.D., FAHA, New York, N.Y.

4 Amyloid-ischemia Interactions: Experimental
Shawn Whitehead, Ph.D., Ottawa, Canada

4:20 Amyloid-ischemia Interactions: Clinical
Eric E. Smith, M.D., M.P.H., FRCPC, Boston, Mass.

4:40 Normotensive Hyperoxia: Experimental
Eng Lo, Ph.D., Charleston, Mass.

5 Normotensive Hyperoxia: Clinical
Marc Fisher, M.D., FAHA, Worcester, Mass.

5:20 Discussion

Session V: Concurrent D
Oral Abstract Presentations: Intracranial Occlusive Disease
Room RO-2

Moderator: E. Sander Connolly, Jr., M.D., New York, N.Y.

4 C-reactive Protein Gene C1444T Polymorphism Is Associated With An Increased Risk Of Further Ischemic Events In Patients With Symptomatic Intracranial Atherostenoses 36
Juan F. Arenillas, Neurosciences Dep. Germans Trias i Pujol Univry Hosp, Barcelona, Spain; Israel Fernández-Cadenas, Neurovascular Res Lab Vall d'Hebron Univry Hosp, Barcelona, Spain; Carlos A. Molina, Neurovascular Unit. Vall d'Hebron Univry Hosp., Barcelona, Spain; Pilar Chacón, Lipid Res Unit. Vall d'Hebron Univry Hosp., Barcelona, Spain; Anna Rosell, Anna Penalba, Neurovascular Res Lab Vall d'Hebron Univry Hosp., Barcelona, Spain; Pilar Delgado, Marc Ribó, José Álvarez-Sabín, Neurovascular Unit. Vall d'Hebron Univry Hosp., Barcelona, Spain; Joan Montaner, Neurovascular Res Lab Vall d'Hebron Univry Hosp., Barcelona, Spain

4:12 Relationship of Site Experience with Clinical Outcomes in Patients Undergoing Intracranial Stenting in the NIH Multicenter Wingspan Registry 37
Fadi Nahab, Emory University, Atlanta, Ga.; Osama O. Zaidat, Medical College of Wisconsin/Froedtert Hospital, Milwaukee, Wis.; Michael Lynn, Marc I. Chimowitz, Emory University, Atlanta, Ga.; for the NIH Multi-center Wingspan Intracranial Stent Registry Study Group

4:24 Analysis of Recurrent Ischemic Events Following Successful Therapy with the Wingspan System 38
Babu G. Welch, UT Southwestern Medical Center, Dallas, Texas; Neuroendovascular Research Collaboration

4:36 Safety and Efficacy of Endovascular Thrombectomy in Patients with Abnormal Hemostasis: Pooled Analysis of the MERCI and Multi MERCI Trials 39
Raul G. Nogueira, Massachusetts General Hospital, Boston, Mass.; on Behalf of the MERCI and Multi MERCI Writing Committee

4:48 US Multi-Center Experience with the Wingspan Stent System for the Treatment of Intracranial Atheromatous Disease: Periprocedural Results for 156 patients 40
Peter Rasmussen, Cleveland Clinic Foundation, Cleveland, Ohio; Neuroendovascular Research Collaboration

5 Natural History of Asymptomatic Restenosis following Endovascular Treatment of Symptomatic Intracranial Stenosis Does Not Support Retreatment 41
Haitham Hussein, Zeenat Qureshi Stroke Research Center University of Minnesota, Minneapolis, Minn.; Mohammad Abdelmoula, UMDNJ, Newark, N.J.; Adnan I. Qureshi, Zeenat Qureshi Stroke Research Center University of Minnesota, Minneapolis, Minn.

5:12 Treatment of Moyamoya Disease in the Adult Population with Indirect Cerebral Revascularization Utilizing Pial Synangiosis 42
Edward R. Smith, Ronald T. Grondin, R. Michael Scott, Children's Hospital Boston, Boston, Mass.

5:24 Discussion

Session V: Concurrent E
Oral Abstract Presentations: In-Hospital
Hall B 2-2

Moderators: Jin-moo Lee, M.D., Ph.D., Saint Louis, Mo.
Lee H Schwamm, M.D., FAHA, Boston, Mass.

4 Blood Pressure in Acute Stroke is Inversely Related to the Extent of Collaterals 43
David S. Liebeskind, Sidney Starkman, Kwang Deog Jo, Arbi G Ohanian, James W. Sayre, Susan Yun, Doojin Kim, Latisha K. Ali, Bruce Ovbiagele, Amytis Towfighi, Samir H. Shah, Reza Jahan, Gary R. Duckwiler, Fernando Vinuela, Jeffrey L. Saver, UCLA, Los Angeles, Calif.

4:12 Outcomes of Moderate Hypothermia for Survivors of In-Hospital and Out-of-Hospital Cardiac Arrest 44
Richard A. Bernstein, Andrew M. Naidech, Northwestern Medical School, Chicago, Ill; Julie Garrett, Robin Oakley, Deborah L. Bergman, Northwestern Memorial Hospital, Chicago, Ill.; Mark J. Alberts, Dan J. Fintel, Northwestern Medical School, Chicago, Ill.

4:24 Slow Initiation of Care and Poor Outcomes for Patients Having In Hospital Ischemic Strokes 45
Frank L. Silver, University of Toronto, Toronto, ON, Canada; Jiming Fang, Institute for Clinical Evaluative Studies, Toronto, ON, Canada; Annette C. Robertson, M. Patrice Lindsay, Institute for Clinical Evaluative Sciences, Toronto, ON, Canada; Moira K. Kapral, University of Toronto, Toronto, ON, Canada

4:36 Stroke Response Nurses - Success in Ischemic Stroke Treatment Parallels Increase in Utilization Eight Years' Experience with 24/7 Stroke Response Nurses 46
Barbara L. Mancini, Patricia Lane, Betsy Stagno, Debbie Healy, John Wesley Cochran II, Inova Fairfax Hosp, Falls Church, Va.

4:48 Impact of Dedicated Stroke Response System on In-Hospital Assessment and Outcomes of Patients with Acute Ischemic Stroke 47
Gustavo J. Rodriguez, Sheetal Patel, Mary DuPlessis-Tchida, Adnan I. Qureshi, David C. Anderson, Kamakshi Lakshminarayan, Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, Minn.

5 A Simplified Model for the Assessment of Quality of Stroke Care in Emerging Countries. The Argentinian National Stroke Registry (ReNACer) 48
Luciano A. Sposato, Favaloro Fndn & Argentinian Neurological Society, Buenos Aires, Argentina; María M Esnaola, Hosp Francés & Argentinan Neurological Society, Buenos Aires, Argentina; Rafael Zamora, Hosp de Clínicas, Buenos Aires, Argentina; María C Zurru, Hosp Italiano & Argentinian Neurological Society, Buenos Aires, Argentina; Osvaldo Fustinoni, INEBA & Argentinian Neurological Society, Buenos Aires, Argentina; Gustavo Saposnik, St. Michael's Hosp, London, ON, Canada

5:12 Intravenous Tissue Plasminogen Activator Use Has a Low Risk of Neurosurgical Intervention 49
Aslam M. Khaja, University of Illinois at Chicago, Chicago, Ill.; Sheryl Martin-Schild, Miriam Morales, Andrew D. Barreto, Hen Hallevi, Nicole R. Gonzales, Kachi Illoh, Elizabeth A. Noser, James C. Grotta, University of Texas - Houston, Houston, Texas

5:24 Discussion

5:30 - 7:30 p.m.
Poster Session I/Reception
Hall B 1